Tuesday, March 30, 2021

Is Marijuana Effective for Pain Relief?

 One of the arguments Soros' groups advanced for supposed medical marijuana laws was pain relief.  I have always been skeptical of the medical marijuana claims because it seemed like an excuse for people whose "pain" was often sobriety.  There is enough evidence now that marijuana increases the risk of schizophrenia to be concerned about giving it the stamp of approval that such laws provide.  3/26/21 Medical Xpress:

Researchers from the University of Bath's Centre for Pain Research have contributed to a major international review into the safety and efficacy of cannabinoids when used to treat pain, including chronic pain in children and adults.

Conducted for the International Association for the Study of Pain (IASP) and recently published across 13 linked  in the journal Pain, leading experts from around the world including Dr. Fisher and Professor Eccleston from Bath reviewed existing data into cannabinoids, including for so-called '' and 'medicinal cannabis extracts."

Their findings suggest that although there is preclinical data supporting the hypothesis of cannabinoid analgesia, uncertainties especially in , imply the  for efficacy and safety does not reach the threshold required for the IASP to endorse their general use for pain control. The studies and the statement from the IASP are limited to the use of cannabinoids to treat pain, and not for other conditions for which cannabinoids are used.

Dr. Emma Fisher who led the review of the clinical evidence said: "Cannabis, cannabinoids, and cannabis-based medicines are becoming an increasingly popular alternative to manage pain. However, our review shows that there is limited evidence to support or refute their use for the management of any pain condition. The studies we found were  (high risk of bias) and the evidence was of very low-certainty, meaning that we are very uncertain of the findings and more research is needed."

4 comments:

  1. I live in Michigan, and suffer from chronic migraine headaches. I tried medical marijuana on two different occasions, using the legal route, and I never had any success from the use of it.
    I will say that I never had touched the drug as a young person, for any reason, and never touched it aside from under the medical rules called for with the state of Michigan. I have an older brother who uses it for migraines and swears by it, but he was a heavy pot user before, and so perhaps that has something to do with it.
    I just know that for any chronic pain patient, who has not found relief no matter how many drugs the doctors have used, they will often be willing to try just about anything to get some relief from the constant suffering. I am in the same boat, thus the trial of marijuana on TWO separate occasions.

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  2. Isn't Tommy Chong out there saying it doesn't work for pain? Or am I misunderstanding the clickbait I do not wish to take?

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  3. One of the (very few) advantages to living in California is the access to legal cannabis products. Anybody can score weed anywhere in the US, but what we're seeing now is various cannabinoids being refined and sold separately.

    I don't smoke weed, because I do not care for the effects of Delta 9 THC (the dominant form in marijuana); it makes me edgy and paranoid and groggy the next day. But sometimes my slipped disc pain flares up to such a degree that not even prescription opioid pills will dull it. D9 THC does, and since I know the exact dosage I'm getting (it's on the package!), I can take it in small amounts at intervals until it starts working. OTOH I've never had any noticeable decrease in pain from using CBD; I'm glad it works for many of you.

    Thanks to a legal market, I've been able to try compounds such as THCA, which seems to help some with pain when delivered via a patch, but not orally; CBN, which ends any insomnia; and CBG, which had no effects whatsoever. Delta 8 THC--which seems to legal for sale as a semi-legal (when derived from hemp) product in non-cannabis states--has been profoundly positive in reducing my PTSD. Again, I'm able to use these in precise amounts, because it's regulated and laboratory tested. There are hundreds of cannabinoids identified, but few have been tested, and even fewer have had clinical trials. If this was an opioid, we would just be getting past the "smoked opium and laudanum" stage of development.

    ReplyDelete
  4. One of the (very few) advantages to living in California is the access to legal cannabis products. Anybody can score weed anywhere in the US, but what we're seeing now is various cannabinoids being refined and sold separately.

    I don't smoke weed, because I do not care for the effects of Delta 9 THC (the dominant form in marijuana); it makes me edgy and paranoid and groggy the next day. But sometimes my slipped disc pain flares up to such a degree that not even prescription opioid pills will dull it. D9 THC does, and since I know the exact dosage I'm getting (it's on the package!), I can take it in small amounts at intervals until it starts working. OTOH I've never had any noticeable decrease in pain from using CBD; I'm glad it works for many of you.

    Thanks to a legal market, I've been able to try compounds such as THCA, which seems to help some with pain when delivered via a patch, but not orally; CBN, which ends any insomnia; and CBG, which had no effects whatsoever. Delta 8 THC--which seems to legal for sale as a semi-legal (when derived from hemp) product in non-cannabis states--has been profoundly positive in reducing my PTSD. Again, I'm able to use these in precise amounts, because it's regulated and laboratory tested. There are hundreds of cannabinoids identified, but few have been tested, and even fewer have had clinical trials. If this was an opioid, we would just be getting past the "smoked opium and laudanum" stage of development.

    ReplyDelete