Friday, October 31, 2014
I was watching a very well-done documentary about light pollution The City Dark, that mentioned some off the recent work on the association between light pollution and breast cancer. This study examines how blood from humans exposed to light at night is depleted of malatonin, and it helped breast cancers in rats to grow:
The increased breast cancer risk in female night shift workers has been postulated to result from the suppression of pineal melatonin production by exposure to light at night. Exposure of rats bearing rat hepatomas or human breast cancer xenografts to increasing intensities of white fluorescent light during each 12-hour dark phase (0-345 μW/cm2) resulted in a dose-dependent suppression of nocturnal melatonin blood levels and a stimulation of tumor growth and linoleic acid uptake/metabolism to the mitogenic molecule 13-hydroxyoctadecadienoic acid. Venous blood samples were collected from healthy, premenopausal female volunteers during either the daytime, nighttime, or nighttime following 90 minutes of ocular bright, white fluorescent light exposure at 580 μW/cm2 (i.e., 2,800 lx). Compared with tumors perfused with daytime-collected melatonin-deficient blood, human breast cancer xenografts and rat hepatomas perfused in situ, with nocturnal, physiologically melatonin-rich blood collected during the night, exhibited markedly suppressed proliferative activity and linoleic acid uptake/metabolism. Tumors perfused with melatonin-deficient blood collected following ocular exposure to light at night exhibited the daytime pattern of high tumor proliferative activity. These results are the first to show that the tumor growth response to exposure to light during darkness is intensity dependent and that the human nocturnal, circadian melatonin signal not only inhibits human breast cancer growth but that this effect is extinguished by short-term ocular exposure to bright, white light at night. These mechanistic studies are the first to provide a rational biological explanation for the increased breast cancer risk in female night shift workers.There are numerous studies now that show these connections. I am increasingly sympathetic to dark sky ordinances as a public health measure. Another study suggests a connection to heart disease:
Background The purpose of this study was to examine prospectively the relation of shift work to risk of coronary heart disease (CHD) in a cohort of women.Methods and Results An ongoing prospective cohort of US female nurses, in whom we assessed (in 1988) the total number of years during which they worked rotating night shifts (at least three nights per month in addition to day and evening shifts), included 79 109 women, 42 to 67 years old in 1988, who were free of diagnosed CHD and stroke. Incident CHD was defined as nonfatal myocardial infarction and fatal CHD. During 4 years of follow-up (1988 to 1992), 292 cases of incident CHD (248 nonfatal myocardial infarction and 44 fatal CHD) occurred. The age-adjusted relative risk of CHD was 1.38 (95% CI, 1.08 to 1.76) in women who reported ever doing shift work compared with those who had never done so. The excess risk persisted after adjustment for cigarette smoking and a variety of other cardiovascular risk factors. Compared with women who had never done shift work, the multivariate adjusted relative risks of CHD were 1.21 (95% CI, 0.92 to 1.59) among women reporting less than 6 years and 1.51 (95% CI, 1.12 to 2.03) among those reporting 6 or more years of rotating night shifts.Conclusions These data are compatible with the possibility that 6 or more years of shift work may increase the risk of CHD in women.
Thursday, October 30, 2014
An election integrity watchdog group is suing the state of Maryland, alleging that it has discovered massive and ongoing fraudulent voting by non-U.S. citizens in one county. But because of the way that the non-citizens are able to cast votes in elections, the fraud is likely happening in every single county and subdivision across the state. The group believes that the illegal voting has been happening for years.This is why voter ID matters, and why Democrats oppose it.
The group, Virginia Voters Alliance, says that it compared how voters in Frederick County filled out jury duty statements compared with their voting records. The group’s investigation found that thousands of people in Frederick County who stated that they are not U.S. citizens on jury duty forms went on to cast votes in elections. Either they failed to tell the truth when they were summoned for jury duty, or they cast illegal votes. Both are crimes. The same group previously found that about 40,000 people are registered to vote in both Virginia and Maryland.
The October 29, 2014 Idaho World reports some hunters found a case of 1930s era dynamite. One of the hunters was a Vietnam era-soldier and said to the reporter, "I didn't want to be blown up again... it hurts!" Some things I guess once is enough.
I mentioned a couple of weeks back that Houston had subpoenaed sermons of pastors who were opposing the city's new transgendered can use whatever bathroom they want ordinance. This sounds like something King James I might have done. The October 29, 2014 Houston Chronicle reports that the mayor has retreated from the sermon subpoenas and explains that what started this was that the people of Houston had requested a referendum on the ordinance, and the mayor decided that the referendum did not conform to the city charter. I don't know what the city charter requires, but I suspect the mayor knows that the referendum would have failed. Even Houston isn't that liberal. A bit more about the dispute from the October 21, 2014 Christian Post:
The conservative Texas Values Action organization turned in an estimated 50,000 signatures to repeal HERO, well above the 17,269 required by law.I can see how the validity of signatures matters. I can't see how the content of sermons would be relevant to the validity of signatures. This seems like an attempt to intimidate pastors into not preaching the Gospel. The mayor of course, is a lesbian.
City attorney David Feldman concluded that many of the signatures were invalid and thus Texas Values did not obtain the necessary number of valid signatures for a referendum.
Wednesday, October 29, 2014
Some neighnors have some goats which have been getting ,y wife's flower gardens. She would like to inflict pain but not permanent injury to encourage them to her garden alone. She has a slingshot, but wants something with more range and accuracy. Note: goat curry is not the right answer.